Presence of orexin A and orexin 1 receptor in the buffalo prostate
The orexins A and B are two peptides discovered initially in the rat lateral hypothalamus involved in the regulation of some body functions such as food intake, sleep/wake cycle, arterial pressure and heart rate. They interact with two receptors defined “orexin receptors 1 and 2”, the first of which shows high selectivity for orexin A and the second binds both the peptides. In this preliminary study the presence of orexin A and orexin 1 receptor in the prostate of the buffalo Bubalus bubalis has been described utilizing the immunohistochemical avidin-biotin technique. The orexin A- and orexin 1 receptor- positive prostatic cells are very numerous and belong to the normal exocrine cytotype which makes up the glandular parenchyma. The role played by orexin A in the genital tract is poorly known. The peptide is retained to stimulate testosterone secretion and to inhibit spermatogonia proliferation in the rat testis.
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Orexin A, Orexin 1 receptor, Prostate, Buffalo
the Italian Journal of Animal Science [eISSN 1828-051X] is the official journal of the Animal Science and Production Association and it is published by PAGEPress®, Pavia, Italy. Reg. Pavia, n. 2/2010-INF. All credits and honors to PKP for their OJS.